Research Opportunity Number: CBE-01
Project Title: Machine Learning of Polymer-Enzyme Interactions
Project Summary: Polymer-protein hybrids are of increasing interest due to their ability to bolster protein stability in a wide range of non-native environments, making them more useful in industrial applications or as therapeutics. In this project, we aim to use a combination of molecular simulation and machine learning to design novel copolymers to stabilize enzymes exposed to thermal stress.
Student Roles and Responsibilities: Student will assist graduate student in the acquisition of data from molecular simulation and the development of machine learning models the predict enhancements in enzyme activities upon exposure to adverse conditions, as a function both polymer and enzyme chemistry.
Additional Considerations: Start and end dates are flexible, but the student should be available at least 20 hours/week.
Department/Institute: Chemical and Biological Engineering
Faculty Sponsor: Michael A Webb
Participation Dates: July 6 - August 31, 2022
Number of Internships Available: 0-1
Application Deadline: March 15, 2022, midnight eastern daylight time