It might not look like much — a plastic box that fits in the hand, with tiny tubes jutting out the top and bottom. Too simple to be cutting edge. Too humble to save so many lives.

But for 20 years, researchers in Robert Prud’homme’s lab have fine-tuned this little box that has revolutionized drug manufacturing, enabling everything…

Eight new interdisciplinary research projects have won seed funding from Princeton University’s Schmidt DataX Fund, marking the third round of grants undertaken by the fund since 2019. The fund, supported…

Two years ago, molecular biologist Zemer Gitai and his research group announced that they had discovered an antibiotic that simultaneously pierced through a disease's defenses while poisoning it from within, like a poison-tipped arrow. And better yet, it was not susceptible to antibiotic resistance.

Discovering the “poisoned arrow"…

Chemists tend to think of the human body as operating out of a sense-and-respond paradigm. For example, you eat sugar, the pancreas senses the intake, and it responds by releasing the hormone insulin to keep your glucose levels in check.

Scientists have long wondered whether there is a similar regulatory strategy for clearing other…

During animal development, specific genes become active in different cells at exact times in order to produce all the tissues and structures of the body. This exquisite genetic choreography is made possible by multiple layers of organization built into organisms’ DNA.  

Now, new research from the laboratory of Princeton scientist

The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing technologies frequently result in unwanted mutations or can fail to introduce any changes at all. These problems have kept the field from reaching…

Researchers at Princeton University have built the world's smallest mechanically interlocked biological structure, a deceptively simple two-ring chain made from tiny strands of amino acids called peptides.

In a paper published August 23 in Nature…

A method that enables the storage and transport of vaccines and life-saving drugs at room temperature, eliminating the need for expensive refrigeration or freezing, is one of 12 technologies selected for development through the Philadelphia-based University City Science Center. The Science Center’s QED Proof of Concept program connects…

Princeton’s Forward Fest — a virtual public conversation series and a monthly highlight of the University’s yearlong A Year of Forward Thinking community engagement campaign — was held on Thursday, March 18, at 3:30 p.m., with a…

Researchers at Princeton have determined how five cellular proteins contribute to an essential step in the life cycle of hepatitis B virus (HBV). The article describing these findings appeared March 11, 2021 in the journal Nature Communications.

Viruses…