Are obesity, diabetes, cardiovascular illnesses and more the result of a “mismatch” between the meals we eat and the foods our bodies are prepared for?
The “mismatch hypothesis” argues that each of our bodies has evolved and adapted to digest the foods that our ancestors ate, and that human bodies will struggle and largely fail to metabolize a radically new set of foods.
A study of more than a half-million people in India who were exposed to the novel coronavirus SARS-CoV-2 suggests that the virus’ continued spread is driven by only a small percentage of those who become infected.
Princeton researchers are making key contributions toward developing a promising new treatment for the widespread and devastating diseases toxoplasmosis and malaria.
The Princeton scientists specialize in preparing the drug compound into a medicine that is both safe and effective for humans and able to reach its intended sites of action in the body in sufficient doses.
A Princeton team has developed a class of light-switchable, highly adaptable molecular tools with new capabilities to control cellular activities. The antibody-like proteins, called OptoBinders, allow researchers to rapidly control processes inside and outside of cells by directing their localization, with potential applications including protein purification, the improved production of biofuels, and new types of targeted cancer therapies.
Researchers at Princeton University have developed a systematic approach for evaluating how the microbial community in our intestines can chemically transform, or metabolize, oral medications in ways that impact their safety and efficacy. The new methodology provides a more complete picture of how gut bacteria metabolize drugs, and could aid the development of medications that are more effective, have fewer side effects, and are personalized to an individual’s microbiome.
A National Science Foundation grant will support Princeton researchers studying how COVID-19 may be spread by people without symptoms through everyday social interactions involving breathing and speaking.
Catching COVID-19 isn’t all-or-nothing, says virus researcher Caroline Bartman in the latest episode of Princeton University’s “We Roar” podcast. Instead, it’s more like a poison: while a tiny amount of most toxins might just make you queasy, a heaping spoonful would be deadly. And like lead poisoning from old pipes, the dose accumulates over time.
Three research endeavors aimed at fundamental challenges in health, information technology and water conservation have been selected for funding through the Eric and Wendy Schmidt Transformative Technology Fund.
In just six weeks, from March 19 to May 1, an international team of physicists and engineers led by Princeton’s Cristian Galbiati brought a ventilator from concept to FDA approval.
The U.S. Food and Drug Administration announced on Sunday, May 3, that the Mechanical Ventilator Milano (MVM) is safe for use in the United States under the FDA’s Emergency Use Authorization, which helps support public health during a crisis.
