A study published in the journal Nature Microbiology identified factors that the hepatitis B virus uses when establishing long-term infection in the liver. The findings could help lead to treatment strategies for chronic HBV infection, a condition that increases the risk of developing liver cancer and is responsible for almost 900,000 deaths worldwide each year. Continue Reading on the Discovery: Research at Princeton blog →
- Tuesday, Mar 10, 2020
- Thursday, Mar 5, 2020
When corporate partners in the Princeton Catalysis Initiative sat down two years ago with David MacMillan, they presented him with a biological challenge at the heart of potential cancer medicines and other therapeutics: which proteins on a cell’s surface touch each other?
- Thursday, Mar 5, 2020
Researchers at Princeton University have revealed the inner workings of a gene repression mechanism in fruit fly embryos, adding insight to the study of human diseases.
- Wednesday, Feb 12, 2020
Optimeos Life Sciences, a startup founded by two Princeton University faculty members, has reached agreements with six pharmaceutical companies to develop therapeutics using a Princeton-developed drug delivery technology. The collaborations have the potential to improve the effectiveness of medications for the treatment of diseases, ranging from cancer to diabetes.
- Wednesday, Feb 5, 2020
Using sophisticated algorithms to explore regions of the genome whose roles in cancer have been largely uncharted, an international team of researchers has opened the door to a new understanding of the disease’s genetic origins.
- Wednesday, Jan 15, 2020
Researchers at Princeton University have successfully recreated a key cell-division step in a test tube, uncovering the vital role played by a protein that is elevated in over 25% of all cancers. The two studies, which appear today in the journals Nature Communications and eLife, are from the laboratory of Sabine Petry, assistant professor of molecular biology. Read more at the Discovery: Research at Princeton blog.
- Wednesday, Jan 8, 2020
A new system that uses artificial intelligence to track animal movements is poised to aid a wide range of studies, from exploring new drugs that affect behavior to ecological research. The approach, shown in the video above, can be used with laboratory animals such as fruit flies and mice as well as larger animals.
- Tuesday, Dec 31, 2019
A new approach for discovering antivirals against hepatitis B and E viruses aims to identify new drug candidates for these life-threatening diseases.
- Monday, Dec 16, 2019
One of the first studies to examine the effect of climate change on diseases such as influenza that are transmitted directly from person to person has found that higher temperatures and increased rainfall could make outbreaks less severe but more common, particularly in North America.
- Friday, Dec 13, 2019
The microbial community populating the human body plays an important role in health and disease, but with few exceptions, how individual microbial species affect health and disease states remains poorly understood. A new study by Princeton researcher Mohamed Abou Donia and his colleagues, appearing in the Dec. 13 issue of the journal Science, gives scientists new tools to explore and understand the human microbiome.