Biotechnology

Novel drug could be a powerful weapon in the fight against malaria and toxoplasmosis
Sept. 15, 2020
Author
Written by Adam Hadhazy for the Office of Engineering Communications

Princeton researchers are making key contributions toward developing a promising new treatment for the widespread and devastating diseases toxoplasmosis and malaria.

The Princeton scientists specialize in preparing the drug compound into a medicine that is both safe and effective for humans and able to reach its intended sites of…

New tools catch and release cellular targets at the flip of a light switch
Aug. 18, 2020
Author
Written by Molly Sharlach, Office of Engineering Communications

A Princeton team has developed a class of light-switchable, highly adaptable molecular tools with new capabilities to control cellular activities. The antibody-like proteins, called OptoBinders, allow researchers to rapidly control processes inside and outside of cells by directing their localization, with potential applications including…

Study investigates potential for gut microbiome to alter drug safety and efficacy
June 10, 2020
Author
Written by Catherine Zandonella, Office of the Dean for Research

Researchers at Princeton University have developed a systematic approach for evaluating how the microbial community in our intestines can chemically transform, or metabolize, oral medications in ways that impact their safety and efficacy. The new methodology provides a more complete picture of how gut bacteria metabolize drugs, and could aid…

Princeton engineering team to use NSF RAPID grant to investigate asymptomatic spread of COVID-19, test strategies for prevention
May 18, 2020
Author
Written by Molly Sharlach, Office of Engineering Communications

A National Science Foundation grant will support Princeton researchers studying how COVID-19 may be spread by people without symptoms through everyday social interactions involving breathing and speaking.

Led by Howard Stone,…

‘We Roar’: Like any poison, the coronavirus is deadlier with higher doses
May 15, 2020
Author
Written by The Office of Communications

Catching COVID-19 isn’t all-or-nothing, says virus researcher Caroline Bartman in the latest episode of Princeton University’s “We Roar” podcast. Instead, it’s more like a poison: while a tiny amount of most toxins might just make…

Three innovative projects selected to receive funding from the Schmidt Transformative Technology Fund
May 11, 2020
Author
Written by Catherine Zandonella, Office of the Dean for Research

Three research endeavors aimed at fundamental challenges in health, information technology and water conservation have been selected for funding through the Eric and Wendy Schmidt Transformative Technology Fund.

The funding will support…

FDA approves ventilator designed by particle physics community
May 5, 2020
Author
Written by by Lauren Biron, Fermi National Accelerator Laboratory, and Liz Fuller-Wright, Princeton University Office of Communications

In just six weeks, from March 19 to May 1, an international team of physicists and engineers led by Princeton’s Cristian Galbiati brought a ventilator from concept to FDA approval.

The U.S. Food and Drug Administration announced on Sunday, May 3, that the

Novel technology aims to improve treatment of neurological diseases
April 16, 2020
Author
Written by Catherine Zandonella, Office of the Dean for Research
A recently developed system for turning on the activity of genes could benefit the treatment of a broad range of genetic diseases.
Princeton awards over half-a-million dollars in funding for rapid, novel and actionable COVID-19 research projects
April 10, 2020
Author
Written by Catherine Zandonella, Office of the Dean for Research

With the aim of accelerating solutions to the challenges of the COVID-19 pandemic, Princeton has awarded University funding for seven new faculty-led research initiatives with strong potential for impact.

The funding enables faculty and their teams to address crucial questions in biomedical, health-related and fundamental science, as…

Researchers identify factors essential for chronic hepatitis B infection
March 10, 2020
Author
Written by Department of Molecular Biology

A study published in the journal Nature Microbiology identified factors that the hepatitis B virus uses when establishing long-term infection in the liver. The findings could help lead to treatment strategies for chronic HBV infection, a condition that increases the risk of developing liver cancer and is responsible for almost 900,000 deaths…