Biotechnology

Brangwynne selected as Howard Hughes Medical Institute Investigator
May 23, 2018
Author
Written by Adam Hadhazy for the Office of Engineering Communications

Brangwynne, an associate professor of chemical and biological engineering at Princeton University, is one of 19 new investigators named by the institute on May 23. The distinction is one of the most sought-after awards in biomedical research.

“I’m incredibly honored,” said Brangwynne, the…

Immune cell provides cradle for mammary stem cells
May 17, 2018
Author
Written by Catherine Zandonella, Office of the Dean for Research

A new study finds that one of the toughest characters in the immune system, the macrophage, has a nurturing side, at least when it comes to guarding the developing breast.

The study published online this week in the journal Science found that macrophages play an important role in…

Petry finds missing ingredient to spark the fireworks of life
May 16, 2018
Author
Written by Liz Fuller-Wright, Office of Communications

Most people can name at least a few bones of the human body, but not many know about the cytoskeleton within our cells, let alone the “microtubules” that give it its shape. Now, a group of Princeton researchers has resolved a long-standing controversy by identifying exactly how the body creates these micron-sized filaments.

Using a…

Researchers use light to turn yeast into biochemical factories
March 22, 2018
Author
Written by Lonnie Shekhtman for the Office of Engineering Communications

Scientists have recently learned how to use light to control specific groups of neurons to better understand the operation of the brain, a development that has transformed areas of neuroscience. Researchers at Princeton University have now applied a similar method to controlling the metabolism, or basic chemical process, of a living cell. In a…

A new weapon against bone metastasis? Princeton lab develops antibody to fight cancer
Dec. 19, 2017
In the ongoing battle between cancer and modern medicine, some therapeutic agents, while effective, can bring undesirable or even dangerous side effects. “Chemo saves lives and improves survival, but it could work much better if you eliminate unwanted side effects from it,” said Princeton University cancer researcher Yibin Kang, the Warner-Lambert/Parke-Davis Professor of Molecular Biology.
Hush, little virus, don’t say a word: How Princeton scientists investigate sleeping viruses
Dec. 18, 2017
Princeton scientists are investigating how viruses become latent in the nervous system - and how to prevent it.
Protecting nature, preserving humanity: Assistant professor Robert Pringle
Nov. 17, 2017
Robert Pringle advocates for a global effort to upgrade and enlarge protected areas.
LEDs light the way for better drug therapies
Nov. 9, 2017
David MacMillan’s lab partnered with Merck to develop a new process for creating radioactive versions of drug molecules, a critical step for tracing where the drugs go and monitoring their impact on the body. Previous attempts to create radioactive labels took months, but Dave’s process can do it in less than a day.
Scientists demonstrate path to linking the genome to healthy tissues and disease
Oct. 16, 2017
An international group of researchers, known as the GTEx Consortium, is studying the diversity of genetic roles in maintaining human tissues. Barbara Engelhardt, an assistant professor of computer science, is a lead author on an article by the group published in Nature about how genetic variation affects gene regulation in 44 human tissue types.
Bioinformatics points the way to treating pancreatic cancer
Sept. 22, 2017
A new study that sifted through a vast amount of biomolecular data has significantly advanced our understanding of the genetics of pancreatic cancer and opened up promising new treatment avenues. Ben Raphael, a professor of computer science, was a lead researcher in the computational analysis of the dataset of molecular changes in a large sample of malignant pancreatic tumors from 150 patients.