A Princeton team has developed a class of light-switchable, highly adaptable molecular tools with new capabilities to control cellular activities. The antibody-like proteins, called OptoBinders, allow researchers to rapidly control processes inside and outside of cells by directing their localization, with potential applications including protein purification, the improved production of biofuels, and new types of targeted cancer therapies.
- Tuesday, Aug 18, 2020
- Thursday, Aug 6, 2020
Princeton’s vital research across the spectrum of environmental issues is today and will continue to be pivotal to solving some of humanity’s toughest problems. Our impact is built on a long, deep, broad legacy of personal commitment, intellectual leadership, perseverance and innovation. This article is part of a series to present the sweep of Princeton’s environmental excellence over the past half-century.
- Friday, Jul 31, 2020
A new partnership between the Princeton Catalysis Initiative (PCI) and Genentech, a biotechnology company based in South San Francisco, is enabling several Princeton faculty members to pursue mission-driven collaborations in fundamental research.
- Wednesday, Jul 22, 2020
Clifford Brangwynne, a biophysical engineer who transformed the way scientists see cell biology, has won the 2020 Blavatnik National Award in Life Sciences.
- Thursday, Jul 16, 2020
Water, so ordinary and so essential to life, acts in ways that are quite puzzling to scientists. For example, why is ice less dense than water, floating rather than sinking the way other liquids do when they freeze?
Now a new study provides strong evidence for a controversial theory that at very cold temperatures water can exist in two distinct liquid forms, one being less dense and more structured than the other.
- Wednesday, Jun 24, 2020
Princeton researchers have created a device that can herd groups of cells like sheep, precisely directing the cells’ movements by manipulating electric fields to mimic those found in the body during healing. The technique opens new possibilities for tissue engineering, including approaches to promote wound healing, repair blood vessels or sculpt tissues.
- Tuesday, Jun 23, 2020
Matthew Kunz, an assistant professor of astrophysical sciences at Princeton University and a physicist at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL), has been awarded a National Science Foundation (NSF) five-year grant to research magnetic fields throughout the early universe and to establish a summer school on plasma physics aimed at attracting women and underrepresented minorities to the field.
- Monday, Jun 8, 2020
Audrey Shih entered Princeton with aspirations of using science to protect vulnerable people from allergens. “I have a severe peanut allergy, and I thought I might help come up with a method to detect allergens in food,” said Shih.
After declaring her concentration in chemical and biological engineering (CBE) and beginning her coursework in the department, “my interest shifted more toward materials science and the more physical than biological side of CBE,” she said.
- Thursday, May 21, 2020
Spurred by the COVID-19 pandemic, Princeton researchers have developed a diagnostic tool to analyze chest X-rays for patterns in diseased lungs. The new tool could give doctors valuable information about a patient's condition, quickly and cheaply, at the point of care.
- Thursday, May 21, 2020
What can modern engineering learn from an erstwhile jeweler who built the largest masonry dome in existence? The construction of the Florentine duomo by Filippo Brunelleschi has been an engineering marvel for more than 500 years, showcasing ancient techniques that still hold valuable insights for modern engineering. Until now, it has remained a mystery how the master goldsmith and sculptor managed to build the masterpiece that pushes the limits of what is possible to construct even with modern building technologies, and how the masters who followed Brunelleschi carried on the tradition.